Amy E Wright Selected Research

dictyostatin

1/2010	Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.
3/2009	Total synthesis and biological evaluation of novel C2-C6 region analogues of dictyostatin.
12/2008	Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.
10/2008	Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
5/2007	Synthesis and biological evaluation of novel analogues of dictyostatin.

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Amy E Wright Research Topics

Disease

17	Neoplasms (Cancer) 01/2021 - 07/2003
10	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017 - 02/2009
2	Colonic Neoplasms (Colon Cancer) 01/2021 - 11/2016
2	Tuberculosis (Tuberculoses) 12/2019 - 01/2017
2	Adenocarcinoma 01/2017 - 01/2017
1	Triple Negative Breast Neoplasms 04/2021
1	Malaria 03/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Disease Progression 01/2021
1	Inflammation (Inflammations) 02/2015
1	Adenocarcinoma of Lung 03/2007
1	Leukemia 03/2007
1	Sarcoma (Soft Tissue Sarcoma) 03/2007

Drug/Important Bio-Agent (IBA)

8	Biological ProductsIBA 04/2021 - 03/2009
8	Paclitaxel (Taxol)FDA LinkGeneric 02/2011 - 07/2003
5	dictyostatinIBA 01/2010 - 05/2007
4	MacrolidesIBA 01/2017 - 12/2008
3	discodermolideIBA 01/2010 - 05/2007
2	Pharmaceutical PreparationsIBA 03/2021 - 12/2019
2	manzamine AIBA 09/2013 - 10/2011
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2009 - 07/2003
2	AldehydesIBA 03/2009 - 12/2008
1	SurvivinIBA 01/2021
1	dragmacidin GIBA 01/2017
1	didemninsIBA 01/2017
1	EnzymesIBA 01/2017
1	ImmunosorbentsIBA 01/2017
1	LuciferasesIBA 01/2017
1	leiodermatolide CIBA 01/2017
1	theopederin KIBA 01/2017
1	nordidemnin BIBA 01/2017
1	Interleukin-8 (Interleukin 8)IBA 01/2017
1	Gemcitabine FDA Link 11/2016
1	PolyketidesIBA 11/2016
1	leiodermatolideIBA 11/2016
1	Antimitotic AgentsIBA 11/2016
1	CytokinesIBA 02/2015
1	Transcription Factors (Transcription Factor)IBA 02/2015
1	NF-kappa B (NF-kB)IBA 02/2015
1	microsclerodermin AIBA 02/2015
1	Apoptosis Regulatory ProteinsIBA 02/2015
1	Caspase 3 (Caspase-3)IBA 09/2014
1	Proteins (Proteins, Gene)FDA Link 09/2014
1	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 09/2013
1	Adenosine Triphosphatases (ATPase)IBA 09/2013
1	neopetrosiquinone AIBA 11/2011
1	Docetaxel (Taxotere)FDA Link 01/2010
1	lasonolide AIBA 11/2009
1	aphrocallistinIBA 06/2009
1	beta-ketophosphonateIBA 12/2008
1	10,11-dihydrodictyostatinIBA 03/2008
1	neopeltolideIBA 03/2007
1	Cytotoxins (Cytolysins)IBA 07/2003

Therapy/Procedure

3	Therapeutics 03/2021 - 02/2009
1	Immunotherapy 01/2019
1	Drug Therapy (Chemotherapy) 02/2015